Tiny plastic particles, from the micro- to nanoscale, have been routinely detected in water, soil, air, aquatic species, and humans in recent years. As concerns grow over their potential impact on the ...

A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that can lead to leukemia, according to findings published in ...

Co-corresponding authors Jian Xu,PhD, (left) and Min Ni, PhD, (right) and co-first authors Junhua Lyu, PhD, (center left) and Yuannyu Zhang, PhD, (center right) identified and characterized a ...

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into mature red blood cells. Ordinarily, glutamine is broken down by stem cells ...

Polystyrene nanoparticles disrupt red blood cell (RBC) maturation in zebrafish embryos. Nanoparticle exposure increases immature RBCs while reducing mature ones, interfering with heme synthesis.

The production of red blood cells from stem cells has emerged as a transformative approach to address chronic blood shortages and meet the increasing demand for transfusion therapies. By harnessing ...

In their quest for safe, mass-producible artificial blood, geneticists have long struggled. Our limited knowledge of genetic pathways that govern the development of blood has kept us from producing ...

Hemoglobin serves as the essential protein in red blood cells responsible for transporting oxygen from the lungs to tissues throughout the body. When levels fall below normal ranges (typically below ...