Nuclear receptors are popular targets for drug companies searching for new therapeutics for cancer and cardiovascular, metabolic, inflammatory, and other diseases. Indigo Biosciences in State College, ...
Development of both the prostate cancer androgen receptor assay and the multi-cancer DDR micronuclei assay successfully completed for AstraZeneca Results of Eisai Phase 2 pilot study supports the ...
AR changes in circulating-tumor DNA (ctDNA) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with high-dose testosterone. This is an ASCO Meeting Abstract from the 2019 ...
STATE COLLEGE, PA, UNITED STATES, September 24, 2024 /EINPresswire.com/ -- INDIGO Biosciences, a premier provider of innovative cell-based reporter assays, announced ...
We identified 100 patients whose core biopsy and definitive surgical specimens were processed in our hospital. New sections, with core and surgical specimens on the same slides, were stained for ...
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...
The cell signaling switchboard just got a little bigger and a little more intricate: five orphan receptors and 17 candidate peptide ligands have been found to connect with each other. Also, nine ...
Cytokinin receptors play a key role in cytokinin-dependent processes regulating plant growth, development, and adaptation; therefore, the functional properties of these receptors are of great ...
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