DOI: 10.1016/j.xgen.2025.100927 Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

The breakthrough discovery of a powerful new gene editing tool called bridge RNAs has the potential to significantly advance gene therapy and usher in a new frontier in genome design, researchers say.

They then compared the essential lncRNAs to protein-coding genes. With the protein-coding genes, if a gene was essential in one of the five cell lines, it was likely to be essential in others. In ...

Rare cell-free RNAs are emerging as a promising class of biomarkers in liquid biopsies. One of the most cutting-edge future applications will probably lie in real-time monitoring of disease ...

Centromeres are important elements of chromosomes that are responsible for the proper separation of chromosomes during cell division. This function is closely related to appropriate methylation ...

There is a lot more to discover. Batish has looked at the presence of circular RNAs in cancers and soft tissue tumors. More recently, she and colleagues, including Dr. Robert Akins’ team at Nemours ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

"We've known that circular RNAs show up in DNA viruses like Epstein-Barr and the human papillomavirus, but seeing that they are generated by an RNA virus like HIV-1 is incredibly exciting," said ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of ...