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Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...
Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we ...
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress
CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...
13d
News Medical on MSNDetermining the biomarkers and pathogenesis of myocardial infarction combined with ankylosing spondylitis via a systems biology approach
Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI) ...
“Our research shows that many transcription factors need to interact with DNA, protein, and RNA to conduct their normal gene regulation functions.
A new nanotube-based RNA delivery system boosts plant regeneration by switching off a molecule that blocks shoot growth, ...
Transcription factors can increase and decrease gene expression, and sometimes work with protein partners to do so; they tend to have an end that can bind to DNA and another end that can attach to ...
DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...
"In this study, we showed that A-to-I RNA-editing enzymes, whose expression is highly elevated upon viral infection, specifically modify the mRNA of adjacent master transcription factor genes in ...
In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
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