DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time.

Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...

Messenger RNA is a go-between molecule that copies DNA codes for building proteins — a process called transcription — and then delivers the transcripts to the cell’s many protein factories, which are ...

Blocking CTR1 phosphorylation caused the RNA-copying machinery to slow down, resulting in reduced “nascent transcription,” meaning fewer new RNA molecules were being made.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...