The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding ...

NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation. Nature Communications, 2025; 16 (1) DOI: 10.1038/s41467-025-56261-7 ...

“NuFold is the RNA equivalent of AlphaFold. AlphaFold is the computational protein structure prediction method, which got the Nobel Prize in chemistry in 2024,” said Kihara.

Neo-1 is the first model to unify de novo molecular generation and atomic-level structure prediction in a single model, by generating latent representations of whole molecules instead of ...

They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. Abstract no. 511: Early prediction of preterm birth with cell-free RNA ...

The researchers say that is a theme in their results: where oligonucleotide structures obey the most-basic rules—think of adenine-uracil and guanine-cytosine pairing in RNA—AlphaFold 3 makes ...

In benchmark tests, NuFold has outperformed traditional energy-based methods and shown better accuracy in local structure prediction compared to recent deep learning-based approaches.” NuFold will ...