NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation. Nature Communications, 2025; 16 (1) DOI: 10.1038/s41467-025-56261-7 ...

“NuFold is the RNA equivalent of AlphaFold. AlphaFold is the computational protein structure prediction method, which got the Nobel Prize in chemistry in 2024,” said Kihara.

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

Neo-1 is the first model to unify de novo molecular generation and atomic-level structure prediction in a single model, by generating latent representations of whole molecules instead of ...

The researchers say that is a theme in their results: where oligonucleotide structures obey the most-basic rules—think of adenine-uracil and guanine-cytosine pairing in RNA—AlphaFold 3 makes ...

They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. Abstract no. 511: Early prediction of preterm birth with cell-free RNA ...

In benchmark tests, NuFold has outperformed traditional energy-based methods and shown better accuracy in local structure prediction compared to recent deep learning-based approaches.” NuFold will ...