RNA is a fundamental molecule of life that plays diverse structural, functional, and regulatory roles in all organisms and pathogenic viruses. In recent years, the discovery of new classes of RNA ...

The 3D structure of RNA is crucial for unraveling its functions. Here, the authors developed NuFold, an end-to-end deep learning-based approach that predicts all-atom RNA 3D structures from sequences.

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI. Nature Chemical Biology, 2025; DOI: 10.1038/s41589-024-01808-w ...

In cells, RNA letters are normally stitched together into biological data chains with an enzyme—a protein called an RNA polymerase. “Mirroring” the enzyme, could, in theory, also build a reflected ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.