RNA Secondary Structure: The pattern of intra-molecular base pairing that forms elements like hairpins, loops and stems, crucial for the overall three-dimensional shape of the molecule.

Such tools are highly relevant for RNA function annotation and RNA drug discovery. In addition, the team hopes to further improve DRfold’s accuracy in single-chain RNA structure prediction.

The prediction for the RNA secondary structure was implemented as a binary quadratic model (BQM)on a D-wave quantum annealer (QA) with a Hamiltonian designed to optimize the number of non ...

By Vijay Kumar Malesu RhoFold+ delivers a leap in RNA 3D structure prediction, combining speed and accuracy to tackle data scarcity and unlock new possibilities in drug development and synthetic ...

RNAs also have an amazing diversity in structure and function. The importance of RNA was highlighted at the “International Conference of RNA Nanotechnology and Therapeutics.” At the conference ...

This paper culminates years of research on the RNA secondary structure and its role in the regulation of gene expression. We have published an extensive computation-based catalog of potentially ...

To understand the function of an RNA molecule, similar to the better-known DNA and vital for cell metabolism, we need to know its three-dimensional structure. Unfortunately, establishing the shape ...

In addition, the team hopes to further improve DRfold’s accuracy in single-chain RNA structure prediction. One of the inherent barriers stems from the limited availability of experimental RNA ...