In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

Initiation Transcription begins with the binding of RNA polymerase to a specific sequence of DNA called the promoter. Promoters are located upstream of the gene and contain recognition sites for the ...

Image Credit: tigerder/Shutterstock RNA-dependent RNA polymerase (RdRp) is a key enzyme for SARS-CoV-2 genomic replication and transcription and, thus, for viral replication.

CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...

It takes a whole village of protein helpers to unwind DNA and prepare it for transcription. But the star is Pol II (RNA polymerase II), a giant multicomplex that moves along a DNA strand helping it ...

RNA molecules perform essential cellular functions including gene regulation, protein synthesis, and genome defense. These diverse biochemical activities frequently depend on RNA secondary and ...

Using a drug to freeze RNA polymerase II on Drosophila DNA, researchers found that transcription could not continue.

RT-PCR, or reverse transcription polymerase chain reaction, is a standard tool used to detect RNA from viruses, such as ...