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DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...
In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
The candidates are sourced from Arnatar’s next-gen RNA discovery engine, dubbed DARGER for dual-functional antisense RNA for ...
RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...
Similar to the way the caps on the ends of a shoelace prevent it from fraying, telomeres—regions of repetitive DNA sequences ...
“Most RNA molecules are synthesized independently and here we uncovered a dual function mRNA that can be used to produce a protein or to make a noncoding telomerase RNA, which is really unique.
RNA molecules can undergo chemical modifications—the addition of specific chemical groups—which alter their function and behavior without changing the underlying nucleotide sequence.
Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases attached in a planar array. These arrays, known as G-tetrad, are connected via Hoogsteen base pairings.
Furthermore, these tools can be used to study the biological functions of RNAs, particularly non-coding RNAs, and design novel RNA experiments using predicted models which follow the ...
San Diego-based Avidity aims to treat FSHD by silencing the culprit gene. Its therapy, formerly known as AOC 1020 and now renamed delpacibart braxlosiran (del-brax), is part of a new class of RNA ...