DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

“Most RNA molecules are synthesized independently and here we uncovered a dual function mRNA that can be used to produce a protein or to make a noncoding telomerase RNA, which is really unique.

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Researchers have developed a new way to study how biochemical processes can impair the immune system’s ability to recognize ...

Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases attached in a planar array. These arrays, known as G-tetrad, are connected via Hoogsteen base pairings.

RNA molecules can undergo chemical modifications—the addition of specific chemical groups—which alter their function and behavior without changing the underlying nucleotide sequence.

For example, RNA viruses such as SARS-CoV use the ER for replication. The researchers were able to significantly suppress viral loads by specifically overstressing the ER.

San Diego-based Avidity aims to treat FSHD by silencing the culprit gene. Its therapy, formerly known as AOC 1020 and now renamed delpacibart braxlosiran (del-brax), is part of a new class of RNA ...

The candidates are sourced from Arnatar’s next-gen RNA discovery engine, dubbed DARGER for dual-functional antisense RNA for ...