This can lead to misunderstandings about RNA editing in the brain if we only study postmortem tissues," said Miguel Rodríguez de los Santos, PhD, co-first author of the study and a postdoctoral ...

In humans and fruit flies alike, RNA editing prevents autoimmune responses and adjusts protein functions. However, in humans, most editing occurs in non-coding regions, with only a small fraction ...

The ability to correct disease-causing genetic mistakes using genome editors holds great promise in medicine, but it is not ...

Scientists have made a major discovery about ADAR1—a protein that controls RNA-induced immune responses—paving the way for better treatments for autoimmune diseases and cancer immunotherapy ...

If DNA is the set of genetic instructions, RNA is what reads and translates those instructions into making the proteins our cells need. RNA editing, then, is also a type of gene therapy.

Like the find-and-replace feature of a word processor, CRISPR-based engineering allows scientists to quickly and efficiently edit DNA sequences with base pair precision. Lauded as the great ...

The challenge with editing ABCA4 is that more than 1,000 mutations to this gene are associated with retinal disorders, making it impossible to develop a gene-editing therapy to address each one.

AIRNA’s therapy for alpha-1 antitrypsin deficiency, or AATD, edits RNA to address the underlying cause of this rare inherited disease. Wave Life Sciences and Korro Bio are both further along in ...

RNA editing is like a proofreading process that happens after your DNA's instructions are copied. Instead of just following the recipe exactly, your cells can make tiny changes to the instructions.

Scientists have made a major discovery about ADAR1—a protein that controls RNA-induced immune responses—paving the way for better treatments for autoimmune diseases and cancer immunotherapy.