For decades, scientists have focused on amyloid plaques—abnormal clumps of misfolded proteins that accumulate between neurons ...

Scientists have long been racking their brains for ways to treat Alzheimer’s disease, the most common type of dementia.

A new Northwestern Medicine study publishing in Nature Medicine suggests a promising alternative to previous attempts to ...

Scientists compared brain tissue from deceased people with Alzheimer’s who received amyloid-beta immunization and those who did not. They found that not only did immune cells called microglia clear ...

The amyloid-β precursor protein (APP) helps to form links between the brain’s neurons. It has been highly studied because its ...

Researchers at Northwestern University have made a breakthrough in identifying a way for Alzheimer's disease to be treated ...

Researchers analyzed the brain of a woman with down syndrome and Alzheimer’s disease, and were shocked to discover that ...

Spatial transcriptomics on human brains parsed microglial reactions to amyloid immunotherapy. Both a vaccine and a therapeutic antibody summoned these cells to plaques. Responders expressed TREM2, ...

For more than three decades, scientists have been racing to stop Alzheimer's disease by removing amyloid beta plaques - sticky clumps of toxic protein that accumulate in the brain.