In 1961 the structure of one protein, myoglobin ... Why should fast kinetics provide evidence for folding intermediates when equilibrium tests showed only two-state folding?

Understanding the physical basis for this activity requires knowledge of the equilibrium and kinetic ... such as the folding of regions of a protein around a prosthetic group, or from changes ...

A paper describing the research, which used a combination of computer simulations and refolding experiments to describe the folding kinetics of a protein called phosphoglycerate kinase (PGK ...

(a) A two-state transition independent of protein concentration ... by agitation, the folding/unfolding transition and the aggregation to polymeric states (P) enter an equilibrium, and the ...