In the PRNT assay, four MPXV recoverees exhibited some detectable neutralizing activity. Yet, all exhibited markedly less neutralization than vaccinated donors.

Study: Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses. Image Credit: 18percengrey / Shutterstock.com This news article was a ...

PRNT assays are generally cumbersome. They require many culture plates and five to seven days to obtain results. This affects turnaround times and outcomes. According to Venkataraman, “The ...

Consistent with the binding antibody data, mRNA-1273 vaccination elicited neutralizing antibodies in all eight of these participants, as measured by plaque reduction neutralization (PRNT) assays ...