Amyloid formation involves the conversion of soluble protein species to an aggregated state. Amyloid fibrils of β-parvalbumin, a protein abundant in fish, act as an allergen but also inhibit the in ...

The assembly of small disordered proteins into highly ordered amyloid fibrils in Alzheimer’s and Parkinson’s patients is closely associated with dementia and neurodegeneration. Understanding the ...

A slew of anti-Aβ antibodies have been developed for clinical trials, in hopes that they will spur the immune system to remove amyloid-β from the brain. But might they also shift the dynamic of Aβ ...

A new mathematical model that describes how proteins self-assemble into stacks known as amyloid fibrils could aid the search for drugs to treat diseases like Alzheimer’s and Parkinson’s. The model, ...

When left to their own devices, Aβ42 monomers tend to ignore each other, but add a little bit of the social lubricant into the mix, and the peptides hook up and form fibrils. So claims a May 7 paper ...