Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chat. The study helps find a better drug target for the ...

Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections. The nervous system works because neurons communicate across ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...

A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...