Purpose To identify markers that can predict overall survival in patients with high-grade advanced stage serous adenocarcinomas. Patients and Methods Oligonucleotide array comparative genomic ...

In oligonucleotide-array CGH, a probe of reduced complexity and no repetitive elements is produced by making a PCR-based representation of each genomic DNA sample.

Oligonucleotide microarray (DNA chip)–based hybridization analysis is a promising new technology which potentially allows rapid and cost–effective screens for all possible mutations and ...

Recent advances in CGH technology, including the use of printed oligonucleotide arrays, have enabled reproducible, high-resolution examination of chromosomes with a high level of detail.

The length increases hybridization efficiency relative to standard oligonucleotides, enhancing specificity and improving the signal-to-noise ratio, according to the company. Xuemin Liu, microarray ...

Blocking oligos are synthetic oligonucleotide sequences that hybridize to specific sequences, including adapters, in a sequencing library to prevent cross-hybridization between library fragments.

This study finds that, at low ionic strengths, an electrostatic balance between the concentration of immobilized oligonucleotide charge and solution ionic strength governs the onset of hybridization.

Creyon Bio, an oligonucleotide research specialist with the goal of designing precision medicines, has emerged with $40 million from a series A financing round led by DCVC Bio and Lux Capital ...

Agilent Technologies says it will spend $725 million to double its manufacturing capacity for therapeutic nucleic acids, or oligonucleotides. The project is the latest in a round of industry ...

When chemical approaches for synthesizing longer DNA oligonucleotides plateaued, scientists turned to a one-of-a-kind enzyme.