The discovery of the twisting switch resolves a long-standing question about how the DNA repair protein RNF168, which has a tendency to cause uncontrolled signalling, is switched off. The paper ...

More information: Bruce Stillman et al, Mechanisms for licensing origins of DNA replication in eukaryotic cells, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-025-01587-5 ...

Their findings, which were published March 7 in Science, one of world’s leading scientific journals, not only reveal new details about how secondary DNA structures like G4s can impede DNA replication, ...

"Untangling a DNA replication mystery may lead to new antimalarial drugs." ScienceDaily. ScienceDaily, 2 February 2022. <www.sciencedaily.com / releases / 2022 / 02 / 220202111811.htm>.

A-DNA forms in a shorter, right-handed double helix. The function of this form is to protect DNA. DNA will revert to this type when it's dehydrated. Z-DNA has a left-handed double helix structure.

“Think of DNA as an instruction manual,” Worthey said. “It tells our cells how to form, operate, and interact with their surroundings.” Most DNA is stored in the cell nucleus. A small portion is found ...

Quantum mechanics, which rules the world of the teensy-tiny, may help explain why genetic mutations spontaneously crop up in DNA as it makes copies of itself.

The enormously long genomic DNA molecules in eukaryotic organisms must be tightly folded to fit into the micrometric dimensions of the chromosomes compacted during mitosis to protect the genetic ...

Researchers at the Smithsonian and around the world are working to sequence the genomes of every eukaryotic species on Earth in the next 10 years through the Earth BioGenome Project.