A new study by Dr. Tian Ye's group from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of ...

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells.

Nucleosome breathing from atomistic time snapshots Date: June 9, 2021 Source: Max-Planck-Gesellschaft Summary: Computer simulations visualize in atomic detail how DNA opens while wrapped around ...

A team of researchers at IRB Barcelona have developed an innovative computational model to precisely predict the position of nucleosomes in the genome. The approach combines machine learning ...

This may explain how nucleosome repositioning occurs and provide valuable information for developing drugs to treat genetic diseases. This research is published in Science.

Effect of SMARCB1 deficiency in renal medullary carcinoma (RMC) on genes associated with nucleosome assembly and telomere organization.

Histones serve as slates to a dizzying array of modifications, but researchers are confident they can decipher the epigenetic puzzle. Roughly two meters of DNA gets packed into every cell nucleus in ...

We have measured the effect of the histones in the nucleosome core particle on methylation of purines in nucleosome DNA by dimethyl sulfate. By using 32P terminally labeled nucleosome cores, we have ...

A group including Jonathan Widom at Northwestern University and Eran Segal of the Weizman Institute used sophisticated computer modeling along with experimental approaches to uncover DNA-encoded rules ...

They want to understand the complete picture of PTMs on a given nucleosome. They think nucleosome-level analysis might help them crack the highest levels of the histone code.