The special issue entitled Chemical Biology of Nucleic Acids: Modifications, Interactions, and Therapeutic Applications invites top-level original papers and review articles in a wide range of areas ...

Peptide nucleic acids (PNAs) represent a revolutionary class of synthetic nucleic acid analogues, in which the traditional sugar–phosphate backbone is replaced by a neutral N- (2-aminoethyl ...

Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA ...

A necessary step in the preparation of biomolecules for downstream applications is determining their concentration by photometric methods, once the nucleic acids or proteins are isolated.