Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

In a recent study published in Neuronal Psychiatry, researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix ...

Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM). An interlinked net of proteins and sugars that surrounds brain cells, the ...

In a study published in Cell Stem Cell, researchers led by Profs. DAI Jianwu and ZHAO Yannan from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have ...

The study conducted by Dr. Gerard Marx and Prof. Chaim Gilon combines the theories of the Global Neuronal Network (GNW) and the Tripartite Mechanism of Memory to offer new insights into the ...

Researchers have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu. Controlling the concentration of different ions can ...

Neural circuits are refined by experience with higher plasticity at younger ages. Non-neuronal brain cells, known as astrocytes, were previously seen as passive support cells, but recent research has ...

Extracellular vesicles, once dismissed by researchers as "cell dust," have in the past 15 years grown exponentially in ...