NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New York Jets and Buffalo Bills.

The Buffalo Bills are falling in many NFL power rankings after their disappointing loss to the Philadelphia Eagles.

The Seahawks remain on top of this week's power rankings, but they have to play the red-hot 49ers for the NFC West title Saturday.

The NFL slate of games for Week 17 is set, and most of America will see the Bills host the Eagles in a massive Sunday afternoon showdown

Entering NFL Week 17, the Bills had the best Super Bowl 60 odds of any AFC team at +850 on BetMGM Sportsbook. Philadelphia had the third-best odds at +800. It would not surprise anyone if either team started the playoffs as a top seed in their conference and advanced to the Super Bowl.

New York dominated Las Vegas, to the tune of 34-10. Giants quarterback Jaxson Dart passed for 207 yards, rushed for 48, and had two touchdowns on the ground. Wide receiver Wan'Dale Robins had 11 receptions for 113 yards.

The stakes are high for several teams in the penultimate week of the NFL regular season. Here's how the odds see it going.

The Philadelphia Eagles come in as the NFC East champions, but the Buffalo Bills have work to do to retain their AFC East title when they host this NFL Week 17 matchup. The Eagles (10-5) hit a rough patch and went on a three-game losing skid because of an inconsistent offense but have bounced back to score 60 points in winning their past two games.

The San Francisco 49ers got some disappointing news when the officiating crew was announced for their game vs the Seattle Seahawks.