Diazepam actions in the VTA facilitate social competition and mitochondrial respiration in the NAc. We first studied the effects of an intra-VTA DZP infusion on behavioral and metabolic outcomes ...

The brain's nucleus accumbens (NAC) is a core region of the mesocorticolimbic dopaminergic system. The mesocorticolimbic dopaminergic system plays an important role in addiction. New findings show ...

The brain's nucleus accumbens (NAC) is a core region of the mesocorticolimbic dopaminergic system and is interconnected with the ventral tegmental area (VTA) and the prefrontal cortex.

In normal-diet mice, this NAc→VTA circuit drives hedonic feeding—the kind of eating that happens not because you're hungry, but because something tastes good. In high-fat-diet mice, this ...

The mesolimbic dopamine system, particularly projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc), plays a critical role in food reward processing.