Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

A medical breakthrough in the UK has seen eight babies born each with three genetic parents. This pioneering method is the first bit of proof that it could prevent mitochondrial disease, a genetic ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

In most plants and animals, including humans, mitochondria are inherited exclusively, or nearly exclusively, from the mother. By contrast, paternal transmission is observed only occasionally, and the ...

Researchers have discovered a key molecular process that may contribute to chronic inflammation as we age. If this process can be accurately targeted, it could unlock ways to stay healthier in our ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...