Mast cell activation syndrome (MCAS) is a condition that occurs when the mast cells in your body release too much of a substance that causes allergy-like symptoms. Mast cells are part of your immune ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Mast cells develop from hematopoietic progenitors in response to stem-cell factor (KIT ligand), which is the ligand of the CD117 transmembrane tyrosine kinase receptor, encoded by KIT. CD117 regulates ...

Researchers in Germany have now been able to show that previously underrated immune cells, so-called mast cells, decide at a very early stage of an infection which way the defense has to go. They only ...

Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma, according to a new study. Mast cell precursor ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor that ...

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an allergen, ...

Mast cell activation syndrome is a condition that causes mast cells to release an inappropriate amount of chemicals into your body. This causes allergy symptoms and a wide range of other symptoms.