A new study using mouse models and multi-omics analysis has traced a specific nerve pathway through which prenatal stress ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Gut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail the mechanisms by which these ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...

Chronic urticaria (CU) is a dermatological condition characterized by recurrent wheals (hives), angioedema (deep tissue swelling), or both, persisting for over 6 weeks. 1 Unlike acute urticaria, which ...

In a mouse model of contact dermatitis, preventive application of a cream containing SYM2081 (right image) reduced skin swelling compared to placebo (left image). A new approach to treat rosacea and ...

Magnetoelectric nanoparticles embedded in a hydrogel and delivered by a threaded acupuncture needle activate mast cells under ...

Researchers have created a nanotherapy that selectively targets and shuts down the immune cells responsible for causing an allergic response in mice, preventing anaphylaxis. Able to be tailored to ...

Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers ...