By tracking brain activity, the team found that the “loser effect” relied on a specific group of interneurons in the dorsomedial striatum (DMS), a component of the basal ganglia. These cholinergic ...
Social hierarchies are everywhere—think of high school dramas, where the athletes are portrayed as the most popular, or large companies, where the CEO makes the important decisions. Such hierarchies ...
The cholinergic interneurons were found to be involved in the loser effect, where mice became less dominant after losing competitions, moving down the social rankings. Surprisingly, these same brain ...
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