Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no cell surface ...

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

An internationally recognized leader in molecular pharmacology and neurobiology, Dr. Bohn recently joined USF Health. She is ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

This discovery gives us a new clue into how TAS2R14 works. It's fascinating because the receptor is not just sensing chemicals from outside the cell, like food or drugs, but also 'tasting' what's ...

Image of a cortical neuron (white) expressing serotonin 2A (5-HT2A) receptors (multicolor). New work shows that engaging 5-HT2A receptors inside cells, but not on the cell surface, encourages cell ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Perhaps complex at first glance, in reality synNotch receptors function simply and possess unseen therapeutic potential. SynNotch is a synthetically engineered version of Notch, a receptor protein ...

Researchers have developed a new strategy that allows engineered T cells to recognize and respond to a single tumour antigen ...

Psychedelics belong to a group of compounds called psychoplastogens, which can promote neuronal growth and restore atrophied connections in the brain. This ability makes the molecules promising as ...