This article explores how advances in AI, structural biology, and new drug modalities are transforming “undruggable” proteins ...

A new study maps the biological influences on thousands of plasma proteins, revealing potential disease biomarkers and drug targets, providing hope for more precise, personalized treatments. Study: ...

3D illustration of a ribosome translating RNA into a peptide or protein. Thousands of genes once thought to be noncoding can make small proteins, or peptideins, after all. Credit: Shutterstock After ...

Researchers and physicians alike are interested in identifying biomarkers from minimally invasive samples like blood to aid in disease detection and monitoring. However, so far, most targets observed ...

Missense variants remain a challenge in genetic interpretation due to their subtle and context-dependent effects. While current prediction models perform well in known disease genes, generalizability ...

Researchers used multi-ethnic proteomics and genetic data to identify blood proteins linked to Alzheimer’s risk. They found causal roles for immune-related proteins, highlighting potential diagnostic ...

A small study found no evidence that smoking causes large or consistent shifts in the ocular surface microbiome or tear ...