Similarly, low concentrations of TFV did not prevent HSV-2 replication in dually infected tissues. HSV-2 enhances ectocervical tissue susceptibility to HIV-1 and decreases the anti-HIV potency of TFV.

In HIV-infected patients undergoing antiretroviral therapy (ART), ongoing HIV replication in lymphoid tissues such as the lymph nodes helps maintain stores, or reservoirs, of the virus, a new ...

Despite the success of protease and reverse transcriptase inhibitors, new drugs to suppress HIV-1 replication are still needed. Several other early events in the viral life cycle (stages before ...

If you want to detect HIV in humans, blood is your friend. Unfortunately, the virus levels found in blood aren’t representative of the entire body because replication takes place in the cells ...

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, ...

In a paper published in the Proceedings of the National Academy of Sciences (PNAS), researchers described the intracellular enzyme neutral sphingomyelinase-2 (nSMase2) as a key player in HIV ...

These findings reveal a previously hidden layer of HIV-1's life cycle, shedding light on how the virus enhances its persistence, replication and ability to evade the immune system.

Infection with hepatitis G virus improves survival in patients infected with HIV probably by directly influencing HIV replication.

Drugs used to treat HIV penetrate poorly into lymphatic tissues where most HIV replication takes place and there is persistent low-level virus replication in these tissues according to research.

S100A8 and S100A9 may inhibit HIV by suppressing virus binding to receptors or suppressing HIV replication during reverse transcription after infection.

Two studies, he said, have previously demonstrated that residual virus replication (RVR) may be occurring in the presence of ART, which could be contributing to viral persistence.

Combination of peptides and a protease inhibitor triggered apoptosis, extricating the virus. Researchers have developed a technique to eliminate HIV by targeted killing of only HIV-infected cells ...