Frontotemporal lobar degeneration, as its name implies, involves shrinkage of the frontal and temporal lobes of the brain. Hidden beneath this moniker is a devilish complexity and variability. In some ...

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative ...

The family of Bruce Willis recently revealed that the actor has been diagnosed with frontotemporal dementia, or FTD. While you’ve likely heard of dementia and associate the health condition with aging ...

Frontotemporal dementia (FTD) is a disorder marked by progressive degeneration of the frontal and or temporal lobes of the brain. It is the most common form of dementia in people under 60, and it is ...

Professor of RNA Therapeutics, Governor Paul Cellucci Chair in Neuroscience Research, Founding Director of Frontotempral Dementia Research Center, UMass Chan Medical School Fen-Biao Gao receives and ...

Bruce Willis’s family recently announced that the 67-year-old actor has been diagnosed with a progressive neurodegenerative disorder called frontotemporal dementia (FTD). The grim news helped explain ...

Side-by-side image shows control neurons from the study (left) compared to neurons from the study with the mis-spliced KCNQ2 gene. Protein TDP-43 malfunctions and disrupts the normal splicing of the ...