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Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-10 (10 pages) Mismatch repair (MMR) is a replication-coupled DNA repair ...
Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress
CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...
Researchers at the Smithsonian and around the world are working to sequence the genomes of every eukaryotic species on Earth in the next 10 years through the Earth BioGenome Project.
New DNA modification system discovered in animals, captured from bacteria more than 60 MYA Date: February 28, 2022 Source: Marine Biological Laboratory Summary: In humans and other eukaryotes, two ...
At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.
Untangling a DNA replication mystery may lead to new antimalarial drugs Date: February 2, 2022 Source: John Innes Centre Summary: The function of an enzyme, critical to most forms of life, has ...
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Somatic and germline mutation rates covary linearly across ciliates and mammals, study finds
In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the ...
In the two previously known epigenetic marks in eukaryotes, a methyl group is added to a DNA base, either cytosine or adenine. The team’s newly discovered mark is also a cytosine modification, but ...
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