The thirst for football is so great the schedule release is a three-hour, prime-time broadcast on the NFL Network.

One of the most anticipated days on the 2025 NFL calendar is this week -- the release of the 2025 schedule. The schedule release certainly isn't for everyone, as fans already know the opponents for their favorite team heading into the release.

The Super Bowl champions will open the 2025 NFL season against their most-hated rivals. The Philadelphia Eagles and Dallas Cowboys will play in the league's opening game, kicking off all the action before any other teams take the field.

The matchup is set for the first game of the upcoming NFL regular season with the defending Super Bowl champion Eagles hosting the Cowboys on Sept. 4.

The 2025 NFL schedule drops on Wednesday evening, with the league announcing its full 272-game slate for the upcoming season. And the calendar is chock-full of anticipated matchups, including the Dallas Cowboys playing host to the Kansas City Chiefs in a Thanksgiving special on CBS and Paramount+.