Spray drying is a versatile and rapid technique that can provide companies with a suitable and scalable option to improve the solubility and bioavailability of drug products. CURTO - STOCK.ADOBE.COM ...

For drug compounds trying to make their way from the lab to the market, poor solubility is often the kiss of death. It’s one of the most common reasons for a drug candidate to drop out of the ...

Solid preparations for oral administration for children have the advantages of convenient carrying and good stability, but for children, they are prone to dysphagia. The liquid dosage form for oral ...

The authors demonstrate how melt-extrusion and spray-drying methods can help to prepare solid dispersions of poorly soluble drugs using Eudragit polymers. The number of poorly soluble drugs continues ...

About 40% of marketed drugs are thought to be poorly water soluble. Development efforts might have to be redoubled, however, because between 70 and 90% of drug candidates in the pipeline are believed ...

Representation of three different types of platforms for ionic liquid-based drug development to deliver poorly soluble compounds--Courtesy of Russian Academy of Sciences A new way to develop drugs may ...

Determining aqueous compound solubility has become an essential tool in the early stages of the drug discovery process. Solubility of a compound is important in the Biopharmaceutics Classification ...

A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3000 ...

Only about 4% of candidate drugs reach the market. The main culprits of this failure are due to issues with dosing , exposure and toxicity. Join us as Dr. Paul Leeson shares how improving candidate ...

The encapsulation of medicines into state-of-the-art carriers is determined by their solubility, researchers from Utrecht University and Eindhoven University of Technology have revealed. This provides ...