DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story.

Guanine (G) is one of the four main nucleobases found in the nucleic acids DNA and RNA, along with along with adenine (A), cytosine (C), and thymine (T). It is a purine base, meaning it has a ...

Cytosine is one of the four main nitrogenous bases found in DNA and RNA, along with adenine (A), guanine (G), and thymine (T) or uracil (U). It is a pyrimidine derivative, meaning it has a single-ring ...

News & Views Published: December 2007 Merging the RNA and DNA worlds Irina Artsimovitch & Dmitry G Vassylyev Nature Structural & Molecular Biology 14, 1122–1123 (2007) Cite this article ...

In the process, DNA is transcribed into RNA and then translated into functional proteins that subsequently undergo folding to achieve their correct structure, which is key to proper function.

Home Academics Undergraduate Majors Biochemistry and Molecular Biology Biochemists and molecular biologists study the chemistry of life. This includes protein structure and function, metabolism, and ...

RNA can hybridize to double-stranded DNA in the presence of 70% formamide by displacing the identical DNA strand. The resulting structure, called an R-loop, is formed in formamide probably because of ...

We’ve shown that RtcB splices 3’-PO 4 and 5’-OH ends via a unique chemical mechanism entailing the formation of covalent RtcB- (histidinyl)-GMP and RNA 3’ pp 5’ G intermediates. There is no 5’ kinase ...

Similar to the way the caps on the ends of a shoelace prevent it from fraying, telomeres—regions of repetitive DNA sequences and a protein structure—protect the tips of chromosomes from damage.