This highlights an important preclinical model that could be successful in humans. The notoriously persistent, ...

When they expressed this mutant viral protein in human cells using a system to evaluate polyomavirus DNA replication, they found the virus's genome replication was decreased by 10-fold.

Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously ...

To investigate the potential role of BMCs in this process, the researchers studied adenovirus, a nuclear-replicating DNA virus. Because the adenovirus proteins involved in genome replication are ...

How skin cancer virus outcompetes host cell replication New study sheds light on the fundamental question of how viruses override their host cells' DNA replicating system Date: July 18, 2023 ...

Just three hours after infection, the virus causes a sizeable fraction of molecules involved in human DNA replication to abandon the cell nucleus and enter viral replication compartments.

How? The simple answer is that they hijack the replication machinery of the host cell. Although most viroids and virusoids do not encode proteins, hepatitis D virus does.

Hepatitis D virus hijacks host cell transcription machinery to make copies of its genetic code. Here, we take a look at the steps involved in this process.

In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates hundreds of times. This "unlicensed" replication is not subject to the same quality control and is much ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

By triggering the DNA damage response in a patient, this could dramatically slow viral DNA replication, suppressing the infection, providing us with a novel avenue for possible antiviral treatments of ...