By clarifying how the DNA sequence affects transcription accuracy, the study offers a new perspective on its fidelity, suggesting that errors are not in random locations but are instead influenced ...

Until now, the mechanisms of how the local DNA context affects these errors have not been well understood. The research team developed a theoretical framework that links transcription fidelity to ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

Why some genes are more error-prone: Scientists uncover hidden rule in DNA transcription Study offers map for improving synthetic and therapeutic RNA Peer-Reviewed Publication Rice University ...