How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

Penn State. "New mechanism for terminating transcription of DNA into RNA in bacteria." ScienceDaily. ScienceDaily, 8 May 2021. <www.sciencedaily.com / releases / 2021 / 05 / 210507160000.htm>.

DNA has to be carefully organized and packaged so it will fit into the nucleus of cells; compacted DNA that's been organized with other proteins is known as chromatin. The structure of the genome can ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

With transcription interrupted, gene expression is also interrupted. As a result, many cellular pathways begin to go haywire; they are deprived of the proteins they need for problem-free functioning.

By clarifying how the DNA sequence affects transcription accuracy, the study offers a new perspective on its fidelity, suggesting that errors are not in random locations but are instead influenced ...

The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription, and answer long-standing questions about the initiation mechanism and ...

Why some genes are more error-prone: Scientists uncover hidden rule in DNA transcription Study offers map for improving synthetic and therapeutic RNA Peer-Reviewed Publication Rice University ...