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The cryoEM structure of a RAD51 displacement loop reveals the molecular mechanism of the strand-exchange reaction at the centre of eukaryotic homologous recombination.
Journal Reference: Parth Rakesh Desai, John F. Marko. Molecular Crowding Suppresses Mechanical Stress-Driven DNA Strand Separation. Biophysical Journal, 2025; DOI: 10.1016/j.bpj.2025.04.024 ...
They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...
They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is ...
Scientists find that complex nanopore signals often come from DNA twisting around itself, not knots, reshaping understanding ...
A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to ...
A new study led by researchers at the University of Cambridge, in collaboration with international institutions, has ...
A genetic study conducted by the University of South Carolina and the National Human Genome Research Institute, published in ...