New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications.

In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates hundreds of times. This "unlicensed" replication is not subject to the same quality control and is much ...

This was supposed to give the virus access to the replication machinery it needed. This would mean that TAg would have to be expressed before cells began replicating their DNA.

In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates hundreds of times. This "unlicensed" replication is not subject to the same quality control and is much ...

Recall that DNA-dependent RNA polymerases usually take DNA as a template and convert it into one or another form of RNA. Hepatitis D virus, however, is made up exclusively of RNA.

Study: Human DNA tumor viruses evade uracil-mediated antiviral immunity. Image Credit: Naeblys/Shutterstock Background Ribonucleic acid (RNA) viruses such as human T-cell lymphotropic virus-1 and ...

Hepatitis D “virus”, despite the name, is a virusoid. Like most other virusoids, it depends on host RNA polymerases for replication. Unlike most other virusoids, it encodes proteins of its own.

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...