Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication. Molecular Cell, 2021; DOI: 10.1016/j.molcel.2021.03.003 ...

The cryoEM structure of a RAD51 displacement loop reveals the molecular mechanism of the strand-exchange reaction at the centre of eukaryotic homologous recombination.

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to ...