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Postmitotic myotubes cannot complete DNA replication following forced cell cycle reactivation. Comparative genomic ...
At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA ...
Directed evolution is usually a laborious process that often takes weeks in which proteins rapidly evolve and develop ...
A new study from King Abdullah University of Science and Technology (KAUST), published in Nature, captures the moment DNA begins to unwind, allowing for all the events that follow in DNA replication.
At school, it’s often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA ...
CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...
More information: Tyler M. Maclay et al, The DNA replication checkpoint targets the kinetochore to reposition DNA structure-induced replication damage to the nuclear periphery, Cell Reports (2025).
RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...
More information: Jason Alexander Halliwell et al, Sex-specific DNA-replication in the early mammalian embryo, Nature Communications (2024). DOI: 10.1038/s41467-024-50727-w ...