For the first time, they showed that the “proofreading” portion of the DNA replicating enzyme polymerase epsilon ensured safe termination of replication at damaged portions of the DNA strand ...

The researchers observed that, on average, a single DNA polymerase molecule remained bound to the nucleic acid at the junction for slightly more than one second—far from the continuous binding that ...

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies. For the first time, they showed that the "proofreading" portion of the ...

Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol ε ...

A research group led by the University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial role in ...