Unraveling DNA polymerase’s activity can help scientists better understand DNA replication and repair and explore how these processes fail and lead to diseases, such as cancer. “This finding [happened ...

A new study on genetic sequencing finds that DNA replication is not as accurate as was previously thought, which could impact a range of fields, from medicine to the study of evolution. DNA ...

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the ...

For the first time, they showed that the “proofreading” portion of the DNA replicating enzyme polymerase epsilon ensured safe termination of replication at damaged portions of the DNA strand ...

A 3D representation of a herpes simplex virus enzyme involved in viral replication. Credit: Abraham Lab/HMS [Jonathan Abraham Lab/HMS] ...

When TV shows like CSI: Crime Scene Investigation portray DNA processing in the forensic lab, the results appear instantly with a DNA match wrapping up the case in hours. However, the ...

Protein involved in balancing DNA replication and restarting found USP50 protein helps balance nuclease and helicase activity during critical processes Date: October 14, 2024 Source: University of ...

A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43735-9 ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

The result: the enzymes that transcribe DNA can’t tell the difference between these synthetic base pairs and those found in nature. “In biology, structure determines function,” said Wang.