It has been previously found that non-coding or repetitive patterns of DNA – which make up around half of our genome – could disrupt the replication of the genome.

The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues, such as those of the liver or kidneys. Unlike in organs that ...

Corces and his colleagues identified a gene important for Drosophila development — modifier of mdg1 or mod (mdg1) — that produces two transcripts, one from each DNA strand. Exons I to IV are ...

Further, it can’t accurately predict how non-coding DNA impacts genes that are located more than 100,000 letters away in the genome. Anshul Kundaje, a computational genomicist at Stanford University ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.

The expression of ZNF558 itself is regulated by the size of a non-coding structural element in DNA called a VNTR, short for variable number tandem repeat that is longer in chimpanzees than in humans.

News Release 7-Jul-2016 Extra-coding RNAs regulate DNA methylation in the adult brain The ecRNAs appear to act in memory formation, and may offer a new therapeutic approach to neuropsychiatric ...