DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

CGGBP1 binds to short CGG repeats in gene promoters, recruiting RNA:DNA helicases like DDX41 to ensure proper transcription ...

Dr. Young and lead authors Ozgur Oksuz, Ph.D., and Jonathan E. Henninger, Ph.D., and colleagues discovered that at least half of the approximately 1,600 TFs in the human genome also bind to RNA.

What happens on the atomic scale when DNA transcription is paused has been unveiled for the first time. (Nanowerk News) A detailed picture of what happens when DNA transcription is paused early in the ...

Here, DNA letters are reworked into a “messenger” called RNA, which then shuttles the information to other parts of the cell to make proteins. Scientists have long suspected that transcription may go ...

Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...