The speed of codon translation at the ribosome has a large bearing on the structure of the final protein, with faster rates thought to promote misfolding. Here the authors present a theoretical ...

Upon recognition of a cognate, but not near-cognate, codon in the small ribosomal subunit, this information must be conveyed to the large subunit. By probing conformational changes that occur upon ...

There is a significant association between codon bias and translation efficiency across all endogenous genes in E. coli and 5. cerevisiae but no association between folding energy and translation ...

From the human mouth to cave water to marine sites and the cow gut, alternative codon translation tables led to more intelligible results in a range of environments.

The genetic code is made up of a total of 64 base triplets or codons. At least one codon encodes the information for each of the 20 amino acids used in the synthesis of proteins during translation ...

More information: Roland Tresky et al, TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice, Nucleic Acids Research (2024).

More information: Roland Tresky et al, TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice, Nucleic Acids Research (2024).