Chromatin: Chromosomes are made up of tightly coiled DNA wrapped around proteins called histones, forming a material called chromatin. This compact packaging allows the long DNA molecules to fit ...

Based on these results, the UAB researchers propose that the chromatin filament of the chromosomes folds according to a regular pattern formed by many stacked layers along the axis of the chromosome.

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.

To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division, each chromosome forms a compact X-shaped structure with two rod-like copies.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a ...

The translocation most typically found in mantle cell lymphoma drags a powerful regulatory element into a new area of the human genome.

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according ...

The evolution of chromatin folding patterns alters genome function and developmental programs that drive phenotypic evolution and adaptation to changing environments,” said Nicole Valenzuela, ...